Does exercise with supplements affect menopause symptoms overall in menopause? What 9 studies found

Postmenopausal women did 2 years of resistance and walking exercise with or without soy isoflavones, and exercise groups maintained hip bone density and improved balance compared with control.

Reported an improvementRandomised trial · 351 women · 104 weeks · 2013PostmenopausalCited 62 timesPubMed

Early postmenopausal women with osteopenia doing high-intensity weight-bearing resistance training three times weekly for about 13 months improved spine bone density, lean mass, body fat, strength and menopausal symptoms versus low-intensity controls.

Reported an improvementRandomised trial · 54 women · 56 weeks · 2021Early postmenopausalCited 38 timesPubMed

Early postmenopausal women did periodized high intensity resistance and impact exercise for a year, and spine bone density was maintained versus a significant decline in the non-exercise control group.

Reported an improvementRandomised trial · 128 women · 52 weeks · 2010Early postmenopausalCited 30 timesPubMed

Postmenopausal women did exercise plus Mediterranean diet, with or without soy isoflavones, for 24 months; the soy group showed greater drops in fat mass, glucose, insulin and inflammation markers.

Reported an improvementRandomised trial · 65 women · 104 weeks · 2012PostmenopausalCited 30 timesPubMed

Postmenopausal women did 6 months of mixed exercise with or without phytoestrogens; quality of life scores improved only in the group combining exercise with phytoestrogens, menopausal symptoms unchanged in both.

No difference foundRandomised trial · 40 women · 26 weeks · 2011PostmenopausalCited 21 timesPubMed

Overweight postmenopausal women did 1 year of aerobic and resistance exercise with or without soy isoflavones, and both groups showed similar improvements in quality of life and climacteric symptoms.

Reported an improvementRandomised trial · 31 women · 52 weeks · 2017PostmenopausalCited 13 timesPubMed

In postmenopausal women, 10 weeks of combined aerobic and resistance training reduced climacteric symptoms, with no added benefit from isoflavone supplementation.

Reported an improvementRandomised trial · 32 women · 10 weeks · 2017PostmenopausalCited 12 timesPubMed

In 330 women aged 45-50 with metabolic syndrome, combined exercise therapy, mineral water, vitamins and physiotherapy reduced psychoemotional menopausal symptoms over 6 months versus conventional treatment alone.

Reported an improvementRandomised trial · 330 women · 26 weeks · 2019PerimenopausalCited 2 timesPubMed

Perimenopausal women did six weeks of high-intensity resistance training with or without creatine; creatine was linked to higher sleep consistency and prefrontal oxygenation gains versus placebo.

Mixed resultsRandomised trial · 51 women · 6 weeks · 2026PerimenopausalPubMed