In the authors' words
“At 12 months, statistically significant reductions in estradiol (treatment effect ratio [TER] = 0.93; 95% CI, 0.88 to 0.98) and free estradiol (TER = 0.91; 95% CI, 0.87 to 0.96) and increases in SHBG (TER = 1.04; 95% CI, 1.02 to 1.07) were observed in the exercise group compared with the control group.”
What was measured
- Hormone levels Reported an improvement
About the study
- Type
- Randomised trial
- Who took part
- Postmenopausal, sedentary at entry
- How many
- 320
- How long
- 52 weeks
- Exercise
- Other aerobic exercise
- Cited
- 161 times, per Europe PMC
- PubMed ID
- 20159820
How to read this. Each line is one study, summarised in plain language from its PubMed abstract, with the authors' own sentence underneath on the study page. A count of studies is not a verdict: trials differ in size, length and quality, and a result in one group of women may not hold in another. Nothing here is medical advice.
Summaries are generated, then checked by machine against the abstract they came from; any summary that could not be matched word for word was left out. Our clinical lead is reviewing the summaries topic by topic, and this note will change when that is done. Corpus last refreshed 2026-11-03. Spotted a mistake? Tell us and we will fix the summary or remove the study.
Similar studies
- A meta-analysis of six RCTs in inactive postmenopausal women found combined exercise and reduced calorie diet, lasting 16 to 52 weeks, lowered estrogen and testosterone levels more than exercise alone.
- A meta-analysis of resistance and aerobic training in postmenopausal women found exercise significantly increased IGF-1 and decreased IGFBP-3 levels.
- A network meta-analysis of 39 trials in postmenopausal women with overweight or obesity found resistance training lowered CRP most, combined training lowered IL-6 and TNF-alpha, and leptin did not change.
- Sedentary, overweight postmenopausal women did 12 months of moderate exercise; at 3 months serum estrogens declined versus controls, but effects were largely limited to women who lost body fat.