In the authors' words
“Our findings indicate that a caloric restriction weight loss diet with or without exercise reduces biomarkers of inflammation in postmenopausal women, with potential clinical significance for cancer risk reduction.”
What was measured
- Inflammation Reported an improvement
About the study
- Type
- Randomised trial
- Who took part
- Postmenopausal, overweight or obesity
- How many
- 438
- How long
- 52 weeks
- Exercise
- Other aerobic exercise, Exercise with diet
- Cited
- 193 times, per Europe PMC
- PubMed ID
- 22549948
How to read this. Each line is one study, summarised in plain language from its PubMed abstract, with the authors' own sentence underneath on the study page. A count of studies is not a verdict: trials differ in size, length and quality, and a result in one group of women may not hold in another. Nothing here is medical advice.
Summaries are generated, then checked by machine against the abstract they came from; any summary that could not be matched word for word was left out. Our clinical lead is reviewing the summaries topic by topic, and this note will change when that is done. Corpus last refreshed 2026-11-03. Spotted a mistake? Tell us and we will fix the summary or remove the study.
Similar studies
- A meta-analysis of 32 studies in postmenopausal women found aerobic, resistance and combined exercise training reduced inflammatory markers IL-6, TNF-alpha and CRP, and increased adiponectin, versus control.
- A network meta-analysis of 39 trials in postmenopausal women with overweight or obesity found resistance training lowered CRP most, combined training lowered IL-6 and TNF-alpha, and leptin did not change.
- Postmenopausal breast cancer survivors cycling three times weekly for 15 weeks showed improved heart rate recovery and a non-significant drop in C-reactive protein versus controls.
- A 6-month aerobic exercise program in overweight postmenopausal women with elevated blood pressure increased fitness and reduced weight and waist circumference but did not change blood pressure or lipid or inflammatory markers.