In the authors' words
“After 24 months, women randomised to PA intervention (arms #2 + #3) showed significant lower level of leptin (37.5% lower) and resistin (65.6% lower) compared to the control group (arms #1 + #4).”
What was measured
- Hormone levels Reported an improvement
About the study
- Type
- Randomised trial
- Who took part
- Postmenopausal
- How many
- 234
- How long
- 104 weeks
- Exercise
- General physical activity, Exercise with diet
- Cited
- 7 times, per Europe PMC
- PubMed ID
- 36454365
How to read this. Each line is one study, summarised in plain language from its PubMed abstract, with the authors' own sentence underneath on the study page. A count of studies is not a verdict: trials differ in size, length and quality, and a result in one group of women may not hold in another. Nothing here is medical advice.
Summaries are generated, then checked by machine against the abstract they came from; any summary that could not be matched word for word was left out. Our clinical lead is reviewing the summaries topic by topic, and this note will change when that is done. Corpus last refreshed 2026-11-03. Spotted a mistake? Tell us and we will fix the summary or remove the study.
Similar studies
- A meta-analysis of 18 randomized trials in healthy women found that physical activity programmes reduced circulating estradiol and testosterone levels, independent of menopausal status.
- A meta-analysis of six RCTs in inactive postmenopausal women found combined exercise and reduced calorie diet, lasting 16 to 52 weeks, lowered estrogen and testosterone levels more than exercise alone.
- Over 12 months, overweight postmenopausal women assigned to diet, exercise, or both reported lower estrogen and testosterone levels, with the largest effects in combined diet plus exercise.
- A review of trials and cohort studies in pre and postmenopausal women found physical activity mostly decreased estrogens, progesterone and androgens, and increased sex hormone binding globulin, with small effect sizes.