In the authors' words
“A 2.3 % weight loss over 12 months among overweight/obese women with early-stage breast cancer does not appear to have deleterious effect on bone health, and might even have beneficial effect.”
What was measured
- Bone density No difference found
About the study
- Type
- Randomised trial
- Who took part
- Postmenopausal, breast cancer survivors, overweight or obesity
- How many
- 81
- How long
- 52 weeks
- Exercise
- Exercise with diet
- Cited
- 13 times, per Europe PMC
- PubMed ID
- 26175059
How to read this. Each line is one study, summarised in plain language from its PubMed abstract, with the authors' own sentence underneath on the study page. A count of studies is not a verdict: trials differ in size, length and quality, and a result in one group of women may not hold in another. Nothing here is medical advice.
Summaries are generated, then checked by machine against the abstract they came from; any summary that could not be matched word for word was left out. Our clinical lead is reviewing the summaries topic by topic, and this note will change when that is done. Corpus last refreshed 2026-11-03. Spotted a mistake? Tell us and we will fix the summary or remove the study.
Similar studies
- A meta-analysis of 13 trials, mostly in postmenopausal women losing weight, found exercise plus calorie restriction preserved hip and femoral neck bone density better than diet alone, but not lumbar spine density.
- In 101 postmenopausal women with obesity over 12 months, severe energy restriction caused greater weight and fat loss than moderate restriction but also greater hip bone density loss, with no difference in handgrip strength.
- Overweight postmenopausal women on a 12 week calorie restricted diet with added aerobic and resistance exercise lost more fat and preserved lean mass compared to diet alone.
- Overweight postmenopausal women underwent diet and exercise weight loss programs for up to a year, reporting that weight loss was linked to a modest decrease in total body bone mineral density.