In the authors' words
“CONCLUSION: We do not observe a significant effect of HT + E vs HT alone.”
What was measured
- Bone density No difference found
About the study
- Type
- Meta-analysis
- Who took part
- Postmenopausal
- How many
- 585
- Exercise
- Exercise with hormone therapy
- Cited
- 7 times, per Europe PMC
- PubMed ID
- 35325147
How to read this. Each line is one study, summarised in plain language from its PubMed abstract, with the authors' own sentence underneath on the study page. A count of studies is not a verdict: trials differ in size, length and quality, and a result in one group of women may not hold in another. Nothing here is medical advice.
Summaries are generated, then checked by machine against the abstract they came from; any summary that could not be matched word for word was left out. Our clinical lead is reviewing the summaries topic by topic, and this note will change when that is done. Corpus last refreshed 2026-11-03. Spotted a mistake? Tell us and we will fix the summary or remove the study.
Similar studies
- A meta-analysis of 9 trials in postmenopausal women found combining antiresorptive drugs or hormone therapy with exercise improved spine and hip bone density more than exercise alone.
- A meta-analysis of six trials in postmenopausal women found that combining hormone therapy with exercise increased hip and spine bone density more than exercise alone.
- Postmenopausal women taking calcium, with or without hormone therapy, who did supervised weight-bearing and resistance exercise three times weekly for a year had greater bone density gains at some sites than non-exercisers.
- Postmenopausal women aged 49 to 55 took hormone therapy or placebo, each with or without exercise, and researchers found exercise improved bone density mainly in the placebo group, with no added effect when combined with estrogen.