In the authors' words
“Estrogen replacement therapy, which achieves serum estradiol concentrations in the physiologic range for 12 weeks, fails to increase exercise tolerance or improve cardiovascular response to exercise in postmenopausal women.”
What was measured
- Fitness No difference found
- Hormone levels Reported an improvement
- Blood pressure No difference found
About the study
- Type
- Randomised trial
- Who took part
- Postmenopausal
- How many
- 31
- How long
- 12 weeks
- Exercise
- Exercise with hormone therapy
- Cited
- 10 times, per Europe PMC
- PubMed ID
- 8694035
How to read this. Each line is one study, summarised in plain language from its PubMed abstract, with the authors' own sentence underneath on the study page. A count of studies is not a verdict: trials differ in size, length and quality, and a result in one group of women may not hold in another. Nothing here is medical advice.
Summaries are generated, then checked by machine against the abstract they came from; any summary that could not be matched word for word was left out. Our clinical lead is reviewing the summaries topic by topic, and this note will change when that is done. Corpus last refreshed 2026-11-03. Spotted a mistake? Tell us and we will fix the summary or remove the study.
Similar studies
- A meta-analysis of seven trials in postmenopausal women found combined aerobic exercise and hormone therapy lowered systolic blood pressure more than aerobic exercise alone, but exercise alone improved fitness more.
- Postmenopausal women who did 12 months of resistance and weight-bearing aerobic exercise gained lean mass and lost leg fat, regardless of hormone therapy use or changes in hormone levels.
- 14 postmenopausal women, some on hormone therapy, did eccentric leg exercise, and those on hormone therapy showed a greater muscle-building gene response afterward.
- Postmenopausal women did a moderate exercise program with or without estrogen for 6 months, and exercise alone reduced cholesterol and LDL and increased fitness.