In the authors' words
“Administering active vit D3 or vit E for 24 weeks as an adjunct to lower limb home exercises did not yield significant additive effects on symptoms, muscle strength, or physical performance in women with knee OA.”
What was measured
- Joint pain Reported an improvement
- Muscle strength Reported an improvement
- Quality of life No difference found
- Bone density Mixed results
About the study
- Type
- Randomised trial
- Who took part
- Postmenopausal, osteoarthritis or joint pain
- How many
- 80
- How long
- 24 weeks
- Exercise
- Resistance training, Exercise with supplements
- Cited
- 0 times, per Europe PMC
- PubMed ID
- 42888606
How to read this. Each line is one study, summarised in plain language from its PubMed abstract, with the authors' own sentence underneath on the study page. A count of studies is not a verdict: trials differ in size, length and quality, and a result in one group of women may not hold in another. Nothing here is medical advice.
Summaries are generated, then checked by machine against the abstract they came from; any summary that could not be matched word for word was left out. Our clinical lead is reviewing the summaries topic by topic, and this note will change when that is done. Corpus last refreshed 2026-11-03. Spotted a mistake? Tell us and we will fix the summary or remove the study.
Similar studies
- A review of 43 trials in postmenopausal women found exercise, especially resistance training and combined programmes, produced a small but statistically significant increase in bone density versus no exercise.
- A meta-analysis of RCTs found that ground and joint reaction exercise of at least 24 weeks produced small but significant improvements in femoral neck and lumbar spine bone density in postmenopausal women.
- A meta-analysis of randomised trials found at least 6 months of supervised weight-bearing exercise did not significantly improve lower-extremity bone strength in postmenopausal women.
- A meta-analysis of 16 trials in older postmenopausal women found whole-body vibration raised lumbar spine bone density while aerobic exercise lowered it, with no overall effect on femoral neck density.